| ncRNA name | rno-miR-126 |
| ncRNA Category | miRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Rattus norvegicus |
| Tissues/Cell_line | retinas |
| Methods | histologic and immunohistochemical analysis, Western blot, qRT-PCR, TUNEL assay |
| Expression pattern | up-regulated |
| Functional description | Niaspan treatment significantly improved clinical and histopathological outcomes; decreased the expressions of VEGF/VEGFR, VCAM-1/CD45, apoptosis and BRB breakdown, significantly increased tight junction proteins and Ang-1/Tie-2 expressions, as well as increased retinal miR-126 expression compared to non-treatment diabetic rats. |
| PubMed ID | 27225425 |
| Year | 2016 |
| Title | MicroRNA-126 contributes to Niaspan treatment induced vascular restoration after diabetic retinopathy. |
| Drug-related ncRNA | YES (Niaspan) |
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